NONMEM

基本解釋

Here we introduced the clinical application development of NONMEM and analyzed recent ten years of typical internal and external documents.
本文通過對國內(nèi)外近十年來大量運用該法研究的論文進行歸納整理,介紹群體藥代動力學研究中非線性混合效應模型法的臨床應用進展。
Nonlinear mixed effect model(NONMEM) has been widely used in estimating population pharmacokinetics parameters of various drugs.
非線性混合效應模型法廣泛應用于臨床各類藥物的群體藥動學參數(shù)估算。
Nonlinear mixed effect model (NONMEM)
非線性混合效應模型法
Keywords Nonlinear mixed effect model（NONMEM）;Clinical application;Development;
非線性混合效應模型法;臨床應用;進展;
Keywords cyclosporine A;renal transplantation;population pharmacokinetics;NONMEM;Michaelis-Menten model;
環(huán)孢素A;腎移植;群體藥動學;NONMEM;米-曼氏模型;