AS-ODN
基本解釋
- 反義核酸
英漢例句
- Electron microscopy and flow cytometry were used to demonstrate apoptotic changes in AS ODN treated cells. Results Both AS ODNs inhibited proliferation of BGC 823 cells.
應(yīng)用相差顯微鏡、電子顯微鏡、流式細(xì)胞術(shù)等方法，觀察bcl?2 ASODN 誘導(dǎo)BGC?823 胃癌細(xì)胞凋亡的效果。 - The inhibitory effect of partial phosphorothioate AS ODN (BCR-ABL AS ODN or C-MYB AS ODN) was as strong as complete phosphorothioat AS ODN with same sequence on CML cell.
部分硫代化的BCR-ABL AS ODN及C-MYB AS ODN對CML細(xì)胞的抑制作用與完全硫代化的同種AS ODN相當(dāng)，而對正常造血細(xì)胞抑制作用較弱。 - Objective To investigate the efficacy of autologous bone marrow transplantation(ABMT) for patients with chronic myelogenous leukemia(CML) after in vitro purging of the graft with bcr/abl antisense oligodeoxynucleotides(AS ODN).
目的 觀察bcr/abl反義寡核苷酸 (AS ODN)凈化后自體骨髓移植 (ABMT)治療慢性粒細(xì)胞白血病 (CML)的療效。 - AS ODN of XIAP+MRP did not enhance the inhibition expression of XIAP in HL-60/ADR cells but increased the sensitivity of HL-60/ADR cells to DNR significantly as compared with AS ODN of XIAP (P 二者聯(lián)合應(yīng)用與XIAP反義寡核苷酸單獨(dú)應(yīng)用比較;并不能增強(qiáng)對XIAP表達(dá)的抑制作用(P>0.;05);但使HL-60/ADR細(xì)胞對柔紅霉素的敏感性明顯增加(P
- AS ODN of XIAP+MRP did not increase the concentration of DNR nor enhanced the inhibition expression of MRP in HL-60/ADR cells but increased the sensitivity of HL-60/ADR cells to DNR significantly (P 二者聯(lián)合應(yīng)用與MRP反義寡核苷酸單獨(dú)應(yīng)用比較;并不能提高HL-60/ADR細(xì)胞內(nèi)DNR濃度及增強(qiáng)對MRP表達(dá)的抑制作用;卻使HL-60/ADR細(xì)胞對柔紅霉素的敏感性明顯增加(P