Syk

基本解釋

Flag-tagged Syk(L) domains SH2, KD, and IDB(L) were transfected into HEK293 cells, respectively, and their interaction with HDAC1 was detected.
構建帶有FLAG標志的Syk(L)各個功能域質粒,并將其轉染入HEK293細胞中,采用免疫沉淀方法檢測HDAC1與Syk(L)各個功能域之間的結合。
The IDB domain of Syk(L)has complete nuclear translocalization function,which is able to transport cytoplasm protein GFP into nucleus.
Syk(L)的IDB域具有完整的核移位功能,能將融合的胞漿蛋白GFP轉移到細胞核內;
AIM:To evaluate the relationship between spleen tyrosine k in ase(Syk)and the biological charcter of keloid fi broblasts(KFB)based on the research of signal transduction of keloid fibro blasts.
目的:通過瘢痕疙瘩成纖維細胞(KeloidFibroblasts,KFB)信號傳遞的研究,探討脾酪氨酸激酶(SpleenTyrosineKinase,Syk)與KFB生物學性狀改變的關系。
BACKGROUND & OBJECTIVE: Full-length form of spleen tyrosine kinase [Syk(L)] is a tumor suppressor gene in breast cancer, which may translocate into cell nucleus and act as a transcriptional repressor.
背景與目的:全長型脾臟酪氨酸激酶[full-length form of spleen tyrosine kinase,Syk(L)]在乳腺癌中具有抑癌功能,可移位到細胞核內,作為轉錄抑制因子調節(jié)基因的轉錄。
Relationship between hypermethylation of Syk gene in promoter and oncogenesis, metastasis of gastric carcinoma
候選抑癌基因Syk啟動子甲基化與胃癌轉移相關