ampelopsin

基本解釋

Abstract： Objective:To study the inhibitory effect of ampelopsin on melanoma.
摘要：目的：研究蛇葡萄素對黑色素瘤的抑制作用。
Objective: To optimize the preparation of ampelopsin from Ampelopsis Cantoniensis Planch.
目的:優(yōu)選蛇葡萄素的提取工藝。
Contrasting the dacarbazine (DTIC), ampelopsin probably is a potent new antitumor natural drug with high antitumor effect and low toxicity.
與氮烯咪胺比較，蛇葡萄素可能是一種高效低毒的新的細(xì)胞毒型抗腫瘤植物藥
Methods:Using a serologic pharmacological method,the inhibitory effects of different dose of ampelopsin on B16 melanoma cells were evaluated by a MTT assay and a flow cytometry.
方法：以血清藥理學(xué)方法考察不同劑量的蛇葡萄素含藥血清對B16黑色素瘤細(xì)胞的抑制作用，分別用MTT法及流式細(xì)胞術(shù)進(jìn)行評價。
Conclusion:Ampelopsin possibly acts on melanoma B16 cells by original form drug at the period with a peak of the drug concentration,and inhibits the DNA synthesis of B16 cells.
結(jié)論：蛇葡萄素在血藥濃度達(dá)峰期對小鼠黑色素瘤B16細(xì)胞的抑制可能以原型物形式起作用，抑制細(xì)胞的DNA合成。