be down and out

基本解釋

Now that you have a basic idea of what needs to be done, sit down and plan out your strategy.
現(xiàn)在，您有一個需要做什么基本的想法，坐下來計劃你的戰(zhàn)略。
One battalion is out, the Marines are out to the extent that we said they were going to come out, and then four more are coming down and be out by July, just like he recommended.
一個營是，海軍陸戰(zhàn)隊員是在某種程度上我們說他們打算出來，并且四更然后下來和是在7月前，如他推薦了。
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"There are so many things you can't anticipate when you create a new technology, " he says. "Who would have predicted that the Internet would be taking down shopping malls and wiping out newspapers?
“在發(fā)明一個新科技時，有太多的事情你無法預(yù)計”他說：“誰會預(yù)測到互聯(lián)網(wǎng)將擊敗商場、消滅報紙？
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Witnesses say at one point early Friday morning, The chief mediator at the talks, former Mozambican President Joaquim Chissano ordered Mr.Rajoelina to sit down and be quiet when he threatened to walk out.
These signaling proteins play important roles in determining how many cells differentiate down particular pathways and they turn out also to be very useful for treating diseases of those pathways.
這些信號蛋白在決定特定分化路徑上,有多少細胞在分化時起著重要作用,且在治療疾病方面也很有用,同樣也是利用這些機制
耶魯公開課 - 生物醫(yī)學工程探索課程節(jié)選
but the fact is they are intelligent, ambitious,motivated and to be just a pawn in the story of a whole bunch of men fighting it out,rolling around and getting down-and-dirty, while there you are just a vision in a tight cat-suit is just a boring thing."

She might even learn a thing or two about what it means to be down and out.
FORBES: Taxing Mr. and Mrs. Jones