Braf
基本解釋
- 布拉夫
英漢例句
- Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma.
BRAF癌基因突變的激活是皮膚黑色素瘤最常見的基因改變。 - BRAF related molecules in MAPK signal transduction are potential treatment target of MM.
BRAF突變相關的MAPK信號傳導分子是治療惡性黑素瘤的靶點。 - The BRAF mutation found in nevi and melanoma increases the activity of the BRAF protein, prompting cells to multiply abnormally.
BRAF蛋白在調控生長以及分化的信號通路中有重要的作用。而這種突變使得BRAF蛋白的活性增強，進而加速了異常的增殖。 - It's still controversial about the relationship of BRAF mutation with heredity, pre-existing pigment nevi, invasion and prognosis of MM.
此突變與遺傳、預先存在的色素痣、腫瘤侵襲性及預后之間的關系還存在爭論。 - It is recognized now that RAS, ERK, especially BRAF kinase in the MAPK/ERK pathway probably play important roles in the development of MM.
目前認為,該信號轉導路徑中的RAS、ERK,尤其是BRAF激酶在黑素瘤的發(fā)生發(fā)展中可能有重要作用。