frequency locus

基本解釋

Methods A simple, rapid and sensitive poly-nuclear cell assay was used to investigate the frequency of HPRT locus mutation.
方法采用多核細胞法研究腫瘤患者外周血淋巴細胞HPRT基因位點的突變頻率，并與正常人群進行對比。
Conclusion The frequency of HPRT locus mutation may be expected to be a potential biological indicator for cancer risk assessment.
不同種類癌癥患者外周血HPRT基因突變頻率無顯著差異。結(jié)論HPRT基因突變頻率分析可作為患癌風(fēng)險評估的生物學(xué)標(biāo)志。
Conclusion The mutant frequency at HPRT locus can be served as one of the biomarkers for detecting genetic damage of human exposure to environmental and occupational mutagens.
結(jié)論體細胞HPRT基因位點突變頻率可作為各種有害因素對機體遺傳損傷的生物標(biāo)識物之一。