cardiac interstitial fibrosis

基本解釋

ACEI reduces the levels of ACEmRNA directly and significantly inhibits the progression of myocardial interstitial fibrosis and cardiac remodeling.
臼）ACEI可直接下調(diào)ACE測(cè)A表達(dá)，有傚地抑制了心肌間質(zhì)纖維化，阻止心肌重塑的發(fā)生。
CONCLUSION:Myocardial interstitial fibrosis and the reduction of myofibril elements are the major pathological basis for the impairment of cardiac function in patients with DCM.
結(jié)論：DCM患者心肌間質(zhì)纖維化，肌原纖維減少是擴(kuò)張型心肌病心功能損害的主要病理基礎(chǔ)。
CONCLUSION Fluvastatin could inhibit myocardial interstitial fibrosis and improve the cardiac function of diabetic rats, which might be related to the down-regulating of the CTGF expression.
結(jié)論氟伐他汀可逆轉(zhuǎn)糖尿病大鼠心肌間質(zhì)纖維化竝改善心功能，這種作用可能與其抑制CTGF的表達(dá)有關(guān)。

心肌間質(zhì)纖維化
Conclusion:Taken together, pressure-overload can mediate cardiac interstitial fibrosis,increase MMPs activity of LV myocardium and contribute to cardiac dysfunction.
結(jié)論：壓力超負(fù)荷誘導(dǎo)的LV重塑過(guò)程中，伴有明顯的心肌間質(zhì)纖維化、MMPs和心功能異常。