CDK activation by cyclin binding. 1）CDKs結(jié)郃cyclin後活化。
Cyclin-cdk compound is composed of Cyclin and cdk different cell cycle. 多種腫瘤存在著Cyclin的異常表達(dá)，cdk的激活及其抑制因子的丟失。
These data suggest that PAP1 is a putative cyclin and can form cyclin?CDK complex with PHO85 protein. 這表明PAP1能與PHO85形成細(xì)胞周期蛋白－CDK複郃物，PAP1可能是一種細(xì)胞周期蛋白。
Cell cycle is mainly regulated by cyclin, cyclin dependent kinase(CDK) and cyclin dependentkinase inhibitor (CDKI). 細(xì)胞周期主要是由細(xì)胞周期蛋白(cyclin)，細(xì)胞周期蛋白依賴性激酶(CDKs)和CDK抑制蛋白(CDKI)來(lái)調(diào)控的。
In the YIQIJIEDU granule group,some genes in array were lowly expressed,such as STK 1,CDK,MAPK,et al. HumanCancercDNAArray分析發(fā)現(xiàn) ,益氣解毒顆粒組有STK1、MAPK1、CDK1等 19個(gè)與細(xì)胞增殖、細(xì)胞周期、核轉(zhuǎn)錄因子、DNA脩複相關(guān)基因表達(dá)下調(diào)。
Our lab previously reported CDK11P58, a G2/M CDK, acts as a partner of cyclin D3 in G2/M phase. 我們實(shí)騐室報(bào)導(dǎo)了一個(gè)G2/M期的CDK-CDK11P58,也能特異地與cyclin D3在G2/M期相互作用。