LXRs

基本解釋

In this review, we summarize the studies of LXRs, elucidating the signal transduction pathway and target genes related of lipid metabolism and inflammatory response.
闡明脂代謝的信號轉(zhuǎn)導(dǎo)將對以上疾病的防治產(chǎn)生深遠的影響。
Together, these results suggest that LXR can control cholesterol homeostasis through regulating IDOL expression and eliciting IDOL mediated LDLR degradation in vivo.
綜上，這些結(jié)果表明：在體內(nèi)，LXR能夠通過調(diào)節(jié)IDOL表達和激活I(lǐng)DOL介導(dǎo)的低密度脂蛋白受體的降解以實現(xiàn)膽固醇穩(wěn)態(tài)的控制。
Since LXR acts as the body's sensor of a buildup of pathogenic cholesterol, its ability to bind both glucose and oxysterols suggests that LXR may be a link between hyperglycemia and atherosclerosis.
作為機體病理性膽固醇蓄積“監(jiān)控器”的LXR能結(jié)合葡萄糖和氧化型膽固醇，該作用提示LXR可能是連接高血糖癥和動脈粥樣硬化的橋梁。
Keywords LXRs;Skeletal muscle;Glycometabolism;Lipid metabolism;Gene;
核受體;骨骼肌;糖代謝;脂代謝;基因;
The interaction of nuclear receptor LXR and inflammation in mouse brain primary astrocytes
核受體LXR與炎癥反應(yīng)在鼠原代腦星形細胞間的相互影響