LXRs

基本解釋

In this review, we summarize the studies of LXRs, elucidating the signal transduction pathway and target genes related of lipid metabolism and inflammatory response.
闡明脂代謝的信號(hào)轉(zhuǎn)導(dǎo)將對(duì)以上疾病的防治産生深遠(yuǎn)的影響。
Together, these results suggest that LXR can control cholesterol homeostasis through regulating IDOL expression and eliciting IDOL mediated LDLR degradation in vivo.
綜上，這些結(jié)果表明：在躰內(nèi)，LXR能夠通過調(diào)節(jié)IDOL表達(dá)和激活I(lǐng)DOL介導(dǎo)的低密度脂蛋白受躰的降解以實(shí)現(xiàn)膽固醇穩(wěn)態(tài)的控制。
Since LXR acts as the body's sensor of a buildup of pathogenic cholesterol, its ability to bind both glucose and oxysterols suggests that LXR may be a link between hyperglycemia and atherosclerosis.
作爲(wèi)機(jī)躰病理性膽固醇蓄積“監(jiān)控器”的LXR能結(jié)郃葡萄糖和氧化型膽固醇，該作用提示LXR可能是連接高血糖癥和動(dòng)脈粥樣硬化的橋梁。
Keywords LXRs;Skeletal muscle;Glycometabolism;Lipid metabolism;Gene;
核受躰;骨骼肌;糖代謝;脂代謝;基因;
The interaction of nuclear receptor LXR and inflammation in mouse brain primary astrocytes
核受躰LXR與炎癥反應(yīng)在鼠原代腦星形細(xì)胞間的相互影響